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Dr Louise Cramer
Tel: 0044 20 7679 7260
Appointment
  • Senior Research Fellow
  • MRC/UCL Lab for Molecular Cell Bio
  • Faculty of Life Sciences
Biography

Academic background includes:


1987                BSc (joint honours, first class) Chemistry and Biochemistry

                        Imperial College, London


1991                PhD, Cell Biology, Imperial College, London


1991-1996 (Dec)      Human Frontiers postdoctoral fellowship and American Cancer Society senior postdoctoral fellowship, University of California, San Francisco, USA


1997                Scientist, The Randall Institute, Kings College, London, UK

1997               Wellcome Trust Career Development Award

1998-2001      Group leader and Royal Society University Research Fellow: MRC-Laboratory   for Molecular Cell Biology, UCL, affiliated with Kings College, London

2001-2008      Group leader and Royal Society University Research Fellow: MRC-Laboratory for Molecular Cell Biology, UCL

2008-current  Group leader: Laboratory for Molecular Cell Biology: dept. of LMCB, division of Biosciences from 2007; dept. and division of LMCB, from 2014


2001              Royal Society URF competitively renewed to 2006

2002-2003                 1 year maternity leave

2003-2005                 Returned to work part-time (variable % FTE)

2004                Royal Society URF competitively renewed to 2008

2005-2006                 1 year maternity leave

2006 (Nov) – current   Returned to work part-time (70% FTE)

Research Groups
Research Themes
Research Summary

The Cramer lab studies cytoskeleton mechanisms in cell polarity and cell migration. Cell migration is essential for life; required throughout embryo development, and for tissue repair and immunity in both the embryo and the adult. It also contributes to several important diseases, including inflammatory diseases, mental retardation and the spread of cancer. Determining molecular mechanisms controlling cell migration thus promises to provide effective therapeutic strategies for treating disease. The Cramer lab studies how migrating cells reach new territory and how they polarize to activate motility, focusing on activity of actin filament and myosin II proteins that drive these processes. We recently discovered a new mechanism of cell migration – where motility is initiated from the cell rear instead of the cell front. We also recently identified a new process where actin filament disassembly drives cell rear retraction.


 

Teaching Summary

Dr. Louise Cramer is Cell Biology Tutor for the Cell Biology Stream of the MRes Biosciences masters programme (for division of Biosciences, faculty of Life Sciences). Louise is also developing a new MSc in Molecular Cell Biology (for division of MRC-Laboratory for Molecular Cell Biology, faculty of Life Sciences). She also teaches on several second and third year undergraduate modules within the faculty of Life Science and hosts undergraduate project and masters students at the MRC-LMCB. She also organizes and teaches part of the taught element of the MRC-LMCB PhD 4-year programme. Louise is chair of the equipment committee and responsible for teaching on the graduate programme committee (division of MRC-LMCB) and on the teaching committee for MRes Biosciences (division of Biosciences).

Academic Background
1990 PhD Doctor of Philosophy – Cell Biology Imperial College of Science, Technology and Medicine
1987 BSc Hons Bachelor of Science (Honours) – Cell Biology Imperial College of Science, Technology and Medicine
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