Dr Laura K. Donovan is a research paediatric neuro-oncologist, with a strong focus in immuno-oncology, molecular medicine, and functional genomics, for the development of novel therapies against paediatric medulloblastomas. Laura has extensive expertise in immunogenomics and how this pertains to candidate target discovery and preclinical modeling for direct translation to clinical therapies. As a previous Fellow at The Hospital for Sick Children (Toronto, CA) and Young Investigator for the SU2C-St Baldricks Foundation Immunogenomics Paediatric Dream Team, she established the use of Chimeric Antigen Receptor T-cells for the effective treatment of paediatric cerebellar brain tumours. This has led to several prominent discoveries including novel locoregional therapeutic delivery for the treatment of medulloblastomas and ependymomas (Nature Medicine, 2020) and a first-in-child clinical trial for posterior fossa A ependymomas (NCT02442297). Laura has also been Team Lead on additional studies, profiling the single cell transcriptome of paediatric medulloblastomas and ependymomas, leading to a better understanding of the tumour-immune microenvironment and the cell of origin of childhood cerebellar tumours, published in Nature, 2019. Dr Donovan was recently awarded the title ‘The Society of International Paediatric Oncology (SIOP) Young Investigator the Year, 2020’.