Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
 More search options
Prof Lucy Walker
Institute of Immunity & Transplantation
UCL Medical School
Royal Free Campus
Prof Lucy Walker profile picture
  • Chair in Immune Regulation
  • Div of Infection & Immunity
  • Faculty of Medical Sciences
Research Summary

The Walker lab is focused on understanding how the immune system is regulated and why it sometimes unleashes its destructive force on tissues of our own body.  In particular we want to understand why the immune system targets the pancreas in certain individuals leading to the development of Type 1 Diabetes.  Part of our research aims to characterise the precise nature of the immune response that drives Type 1 Diabetes (Who are the key cellular players? Which pathways activate them? What factors do they secrete?).  Further projects involve dissecting the regulatory mechanisms that normally operate to keep the immune system in check.  Chief among these is a population of cells termed regulatory T cells that actively suppress autoimmunity in healthy individuals.  We are interested in uncovering the molecular mechanisms that regulatory T cells use to inhibit autoimmune diseases like Type 1 Diabetes.  We believe that a more precise understanding of why autoimmune diseases develop, and of the protective mechanisms that normally prevent this, will open new avenues for treating these conditions.

Please report any queries concerning the data shown on this page to https://www.ucl.ac.uk/hr/helpdesk/helpdesk_web_form.php
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by