My group is currently investigating the genetic basis of pituitary and forebrain development, particularly in relation to the aetiology of disorders of forebrain and pituitary development. We have established the genetic basis of hypopituitarism in a significant number of patients presenting to the Paediatric Endocrinology clinics. We were the first to describe a genetic basis for a disorder called septo-optic dysplasia (SOD) which consists of forebrain, pituitary and eye defects. We have established collaborations with a number of national and international clinical and non-clinical scientists. As a result of these collaborations we have established a large collection of DNA samples from patients with various forms of hypopituitarism.