My research interest is to investigate how gene expression programs are controled by transcription factors, chromatin regulators (Bromodomain and Extra Terminal, BET proteins) and signalling pathways in Th17-mediated inflmmation especially in ocular inflammatory diseases. I am currently applying  molecular, cellular and animal models in a translational approach to address key questions in the role of  BET protein BRD4 in Th17 effector cells. I have already shown that targeting BET proteins ameliorate the inflammation progression in human and mouse Th17 models which was accompanied with a significant down-regulation of Th17 associated genes in response to BET inhibitors. I am currently approaching to studyy the mechanism of Th17 suppression by BET inhibitors and the effects of BET protein inhibition on Th17 master transcription factor function.