Prof Fruttiger's research is focused on vascular development and physiology of the retina, as well as associated diseases, such as Diabetic Retinopathy, Retinopathy of Prematurity, Macular Telangiectasia and Age-related Macular Degeneration. In his laboratory, basic science studies in model systems are complemented by histopathological studies on human post-mortem tissue to learn how model-based insights can be related to clinical findings and translated to therapies. In collaboration with clinicians at Moorfields Eye Hospital his team also use patient phenotyping, genetic information and bio samples to learn more about genetic and molecular mechanisms that drive pathologies in the retina.