Macey is a researcher within the Methodology Conduct Programme at MRC Clinical Trials Unit. She is funded by Health Data Research UK to develop ways to enhance the conduct of clinical trials with routinely collected healthcare data.

Initially trained as a medical biochemist, Macey has worked in different roles within clinical trials (phase 1-4) in industry and academia, beginning in data management, then to trial management, spending five years coordinating large international breast cancer trials at Imperial College London.

Between 2003 and 2015, Macey conducted research in paediatric pharmacoepidemiology and drug safety, latterly as a Teaching and Research Fellow at the Centre for Paediatric Pharmacy Research based at the School of Pharmacy, University of London (now UCL School of Pharmacy). The Centre began in 2002 as a fruitful collaboration between the School, the Institute of Child Health, and Great Ormond Street Hospital for Children, to focus research activities specifically in paediatric pharmacy. During her time at the School, Macey undertook doctoral studies in the use and safety of antidepressants in young people using routinely collected primary care data, and was awarded her PhD in September 2009.  As a Teaching and Research Fellow, Macey participated in four European Consortia to investigate paediatric medicines use and safety, and represented the School in the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP), participating in the Working Group on Guidance for Data Integration; the guidance was later incorporated into the ENCePP’s guide on methodological standards.

In 2015, Macey joined the Comprehensive Clinical Trials Unit (CCTU) to manage a large UK multicentre trial in sexual health (HIPvac) in collaboration with the Mortimer Market Centre. Following the successful completion of HIPvac in 2018, Macey moved teams to set up the CCTU’s largest ever trial to date (OPTIMAS) which aims to recruit approx. 3500 patients with acute ischaemic stroke and atrial fibrillation from >100 hyperacute and acute stroke units in the UK.

Macey began working at the MRC Clinical Trials Unit in September 2019. Her research role within the Trial Conduct Methodology team enables Macey to bring together her extensive experience and knowledge to develop ways to improve access, quality and use of electronic healthcare records to enhance the conduct of clinical trials.