Mine is an expert in patient centric medicine development. Her research focuses on designing advanced drug delivery systems for special patient groups. She has published 100 papers and 4 book chapters. She established CelebrAGE: Celebrating Ageing Innovation Network and took role in significant public engagement activities (Soapbox Science sessions; Tomorrow`s Home: Visions of Home-based Healthcare).

Her research group`s work follows four lines of research:

1.    Novel applications of emerging engineering and digital health technologies for personalised treatments, diagnosis and monitoring: Prof Orlu`s research group utilise a cross-disciplinary approach by bringing the scientific advancements of healthcare engineering into pharmaceutics.

2.    Age-related medicine design and use: Mine`s research team aims to customise medicine design for older patients. The premise of the work is that physiological and functional age should be factored into the development of advanced drug delivery systems. He team exploits pharmaceutical sciences to improve the therapeutic outcomes and adherence of older people to their prescribed medicine.

3.    Targeted oral drug delivery systems for special populations: Mine`s research brings novel understanding to the personalised formulation design by factoring in the physiological and/or drug administration related differences among patient groups.

4.    Drug repurposing: Her research team`s approach into patient centric pharmaceutical design is utilised in translational science to reformulate and optimise the oral bioavailability of repurposed drugs.

Prof Orlu`s research team`s ongoing projects include:

•The application of AI and machine learning techniques to predict the food effect on oral drug absorption (in collaboration with Prof Abdul Basit, UCL SoP)

•The interplay between the drug and special populations` age, sex and gut microbiota (as part of COLOTAN: Boosting advanced doctoral training in innovative colon targeting drugs)

•The utilisation of electrospinning to develop combined therapies for overcoming the challenge of polypharmacy and optimising the multiple drug release profile (in collaboration with Prof Gareth Williams, UCL SoP)

•Lab-on-an-App: AI empowered point-of-care diagnostics for ageing population (in collaboration with Prof Miguel Rodrigues, UCL EEE)

•Exploration of NAD+ boosters` efficacy following reformulation in treating mitochondrial disease (in collaboration with Dr Rob Pitceathly, UCL IoN)