Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
- Senior Lecturer
- Div of Infection & Immunity
- Faculty of Medical Sciences
PhD: The regulation of human cytomegalovirus latency and reactivation in dendritic cells by chromatin remodelling. University of Cambridge (Profs. Sissons & Sinclair)
Post Doctoral Associate: the anti-apoptotic function of virally expressed untranslated RNA. University of Cambridge (Prof. Sinclair)
Presidential Fellowship: Cellular signalling in HCMV latency and reactivation. Novartis, Massachussets, USA (Prof. Compton)
MRC CDA Fellowship: Impact of cellular signalling and viral gene expression of reactivation of HCMV from latency (University of Cambridge/ UCL)
Senior Lecturer: Institute of Immunity & Transplantation, UCL.
It is becoming increasingly clear that throughout latency (from establishment to maintenance and, ultimately, reactivation) there is a complex interplay between the virus and the cell. Our own studies are focus on events that occur during the very early stages of viral entry into the cellular site of latency and the mechanisms that trigger reactivation. In both instances, we are interested in the reliance of host signalling pathways for these processes and, furthermore, the viral mechanisms that contribute to the successful utilisation of these cellular pathways.
Through these studies we hope to further our understanding of the complex interaction between the host and pathogen and,specifically, the intimate relationship persistent viruses have with their host.
My laboratory hosts undergraduate and graduate students (Masters & PhD students) and welcomes applications from students who wish to undertake their graduate research with us. Similarly, we host and support undergraduate students applying for summer vacation scholarships.
|2005||PhD||Doctor of Philosophy – Molecular Virology||University of Cambridge|
|2000||BSc Hons||Bachelor of Science – Molecular Biology||University of Manchester|