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Dr Michael Zandi
Institute of Neurology
Queen Square
Dr Michael Zandi profile picture
  • Honorary Associate Professor
  • UCL Queen Square Institute of Neurology
  • Faculty of Brain Sciences

I trained in medical and veterinary sciences Tripos at Clare College Cambridge (part II in Experimental Psychology with Prof Barry Everitt), clinical medicine at Cambridge with elective as externe in neurology at the Salpêtrière, Paris with Bertrand Fontaine, then general medical training to MRCP(UK). I did my neurology training in Cambridge, Norwich and London, as part of an Eastern Region Neuroscience Fellowship with PhD at Cambridge University in biomarkers of neuropsychiatric lupus and NMDAR encephalitis, with time in the laboratories of Professor Alasdair Coles in Cambridge, and Professor Angela Vincent at Oxford University. Elected FRCP Jun 2018. I have funding support from the UCLH/UCL Biomedical Research Centre.

I am Consultant Neurologist at the National Hospital for Neurology and Neurosurgery, Queen Square, London and Honorary Associate Professor in the University College London Queen Square Institute of Neurology Department of Neuromuscular Diseases.

I run an autoimmune encephalitis and neuroimmunology clinic, and co-chair the weekly UCL Queen Square National Hospital COVID-19 neurology and encephalitis meeting.

With funding from the National Brain Appeal Dr Patricia McNamara and I run a clinical service for those with neurological symptoms and complications of Covid-19, and long Covid.

I work on central nervous system neuroimmunological diseases, particularly autoimmune encephalitis (eg. associated with NMDAR, LGI1 or related autoantibodies, COVID-19 neurology), with a broader research interest in all central and peripheral neuroimmunology, CNS vasculitis and amyloid related angiopathy, neuropsychiatric involvement in systemic lupus erythematosus and related conditions, and the role of inflammation in neurodegenerative disease and in neuropsychiatric disease.

I am a PI on the UCL Neuroimmunology 1.4 study, SINAPPS2, and ENCEPH-IG trials, a member of the UCL repurposing therapeutic innovation network group, and on the steering committee of Coronerve.
Research Summary

We are working on the neurological and psychiatric complications of Covid-19 (with Manji, McNamara, Benjamin, Paterson, Werring and colleagues at UCL, Coronerve UK Group) T cell biology of autoimmune encephalitis (Rachel Brown - MRC funded, Lunn, Morris), neuroimmunology of catatonia (Jonathan Rogers - Wellcome funded, Lewis, David), neuroimmunology of CNS disorders (with Lunn, Hart and colleagues in the Neuroimmunology laboratory at UCL/UCLH). We are supported by the UCL/UCLH NIHR BRC.

Our paper in Brain on the neurological complications of Covid-19 features in the following media and editorials: Guardian, New York Times, This Week in Virology (TWIV), Science, El Pais, Le Figaro, BBC Science Focus with Rachel Brown, The Conversation, BBC feature by Fergus Walsh with Arvind Chandratheva and Michael Zandi, BBC Radio Scotland interview with Ross Paterson, France 5 C dans l’air feature with Michael Zandi, CBS News Hadi Manji, 95bFM New Zealand Radio interview and Radio New Zealand Jasper Morrow, Deutsche Welle Sarah Wiethoff, Jornal da Cultura Brazil Michael Zandi, CNN interviews with Hadi Manji and Michael Zandi, Royal Society of Medicine Hadi Manji, TV3 Catalunya Michael Zandi, MSNBC Michael Zandi, BBC North West Laura Benjamin, New York Times, Nature, Patricia McNamara Irish Times, New Statesman, Dipa Jayaseelan Bloomberg, Guardian.

Teaching Summary

I teach and lecture on UCL Queen Square MSc courses and co-supervise MSc students (Hannah Priday, co-supervised with Prof David Werring and Prof Angela Vincent), previous UCL MSc students Eleanor Taylor (library); David Robaldo (library completed) and Alexis Cassecuelle (lab completed, with Dr Rob Pitceathly); and co-supervise PhD fellows (Dr Rachel Brown and Dr Jonathan Rogers). I lecture also for KCL MSc neuropsychiatry courses and other regional training days.

Selected recent and upcoming invited Lectures

12 October 2017 - Association of British Neurologists autumn meeting, London

21 March 2018 - King's College London Immunopsychiatry meeting, London

25 June 2018 - Royal College of Psychiatrists, Birmingham

20 September 2018 - British Society of Rheumatology Case Based Conference, London

8 October 2018 - Royal College of Psychiatrists Faculty of Old Age Psychiatrists winter meeting, London

19 October 2018 - East Anglian Regional Neurological Association, Norwich

2 November 2018 - British Medical Journal Practical Neurology Masterclass, London

28 Mar 2019 - Queen Square Leading Edge Course, London

24 July 2019 - Camden and Islington Mental Health Trust academic meeting, London

2 Oct 2019 - UCL Institute of Mental Health first symposium: immunopsychiatry, London

15 July 2020 - SINAPPS2 trial webinar, UK

8 August 2020 - McGill University, Montreal

28 August 2020 - Washington University Julius Axelrod Brain series lecture, Washington

4 September 2020 - Eastern Network for Rare Autoimmune Diseases, Stevenage/Cambridge

17 October 2020 - Sociedade de Neurologia da Bahia

27 October 2020 - Henry Stewart Talks

29 October 2020 - Norwegian Neurological Association National Meeting

5 November 2020 - Brain Infections Global Liverpool 5 November 2020

7 December 2020 - Cultura UNAM Festival El Aleph - Festival de Arte y Ciencia Mexico

09-JUL-2019 Honorary Associate Professor Neuromuscular Diseases Queen Square Institute of Neurology, United Kingdom
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