UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data shown on the profile page to:

http://www.ucl.ac.uk/finance/secure/research/post_award
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
 More search options
Dr Philip Stanier
Institute of Child Health UCL
30 Guildford Street
London
WC1N 1EH
Appointment
  • GOSHCC Reader in Cranofacial Developmental Biology and Genetics
  • ICH - Neural Development Unit
  • Dept of Neurosciences & Mental Health
  • Faculty of Population Health Sciences
 
 
Research Summary
My research interests are focussed around identifying the genetic and molecular basis of common birth defects, particularly those affecting neural tube or craniofacial development. Our investigation of mouse models with severe neural tube defects (NTD) led to the discovery that the planar cell polarity pathway (PCP), first described in Drosophila, plays an essential role of in normal and abnormal neural tube development. Current research is investigating PCP genes for their role in human NTD. In addition, we are investigating the contribution of inborn errors of folate metabolism in cohorts of patients with open neural tubes (e.g. spina bifida aperta, anencephaly and craniorachischisis), as well as closed defects (spina bifida occulta). My lab also studies the genetics and cellular mechanism underlying cleft lip and/or palate, with a particular interest in X-linked cleft palate caused by mutations in the transcription factor TBX22.
Academic Background
1990 PhD Doctor of Philosophy St Mary's Hospital Medical School
1985 BSc Bachelor of Science Bristol Polytechnic
Please report any queries concerning the data shown on this page to:

https://www.ucl.ac.uk/hr/helpdesk/helpdesk_web_form.php
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by