Dr Syrris's research career has focused on studying the genetics of inherited forms of cardiovascular disease. He has expertise in gene identification, mutation screening and in vitro functional studies in inherited cardiomyopathy and arrhythmia syndromes.
Major achievements in the last ten years include the identification of novel causative genes for arrhythmogenic right ventricular cardiomyopathy, determination of novel genotype/phenotype correlations in inherited cardiomyopathies and functional work on pathogenic desmosomal gene variants in in vitro cell systems.
More recently, Dr Syrris and the laboratory team have developed next generation sequencing methodology as a routine molecular genetic test for inherited cardiomyopathies, ion channel disease and other arrhythmia syndromes.