The Henriques laboratory was established in 2013 to undertake research combining cell biology, optical physics and biochemistry. The group focuses on biological problems that cannot be addressed with current imaging technology, and thus aims to develop analytical, optical and biochemical approaches to address these questions. In cell biology we aim to understand how viruses enter cells, probing and remodelling membranes, and what are the structural changes viruses undergo during cell-entry, uncoating and morphogenesis. To do so, we are developing new classes of fluorescent probes, high-speed cell friendly Super-Resolution methods and computational modelling approaches that, although designed to answer questions of interest in the lab, will have broad applications in cell biology research.