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Mr Reza Motallebzadeh
Appointment
  • Clinical Senior Lecturer in Renal Transplant Surgery and Honorary
  • Department of Surgical Biotechnology
  • Div of Surgery & Interventional Sci
  • Faculty of Medical Sciences
Biography

Reza Motallebzadeh was educated at Westminster School, London and completed the pre-clinical and clinical Medical Sciences Tripos at St. John's College, Cambridge University. Reza initially trained as a specialist registrar in cardiothoracic surgeon in London, and undertook a research MD at St. George’s Hospital, London University. Reza was always fascinated by immunology and subsequently pursued a career in abdominal transplantation surgery. He completed a PhD (2008-2011) in the Department of Surgery, Cambridge University, to understand the role of tertiary lymphoid organs in chronic allograft rejection, and then went on to do a NIHR Clinical Lecturer post in Cambridge University Hospital investigating the role of germinal centre B cells in alloantibody-mediated rejection. 


Reza joined the Royal Free Hospital as Honorary Consultant Renal Transplant Surgeon and Associate Professor, UCL in September 2017. He is Head of Centre for Transplantation, Department of Renal Medicine, UCL and Deputy Head, Centre for Surgical Innovation, Organ Repair and Transplantation, Division of Surgery and Interventional Science, UCL.



Research Summary

Reza Motallebzadeh directs the basic science and translational academic research from the Transplant Directorate at the Royal Free Hospital and Institute of Immunity and Transplantation, and leads the unit’s clinical renal transplantation trials portfolio.  

 

Reza's laboratory is focused on collaborative, multidisciplinary and translational research in experimental and clinical kidney transplantation. The research themes are underpinned by a commitment to developing innovative collaborations with academic centres and industrial partners to address fundamental questions concerning end-stage kidney disease and kidney transplantation. Reza's clinical research programme similarly utilises a multidisciplinary approach to address key clinical challenges in kidney transplantation and vascular access surgery. These include -


 - Understanding the immune mechanisms underlying development of allograft vasculopathy and chronic rejection in solid organ transplantation, in particular the role of T follicular helper cells.


 - Development of biomarkers for acute and chronic allograft rejection.  


 - Delineating the role of the microbiota in renal transplantation.


 - Developing 3D culture models of renal fibrosis using organoids based on human kidney extracellular matrix scaffolds.

Teaching Summary

1. Module Lead & Course Tutor for the Transplantation Science module of the MSc/MRes Programme in Human Tissue Repair and Surgical and Interventional Sciences (SURG0083: Transplantation Science). 


2. Module Lead & Course Tutor for the Student Selected Component in Transplantation Sciences (MBBS Year 2 SSC: Transplantation Sciences, SSC110).


3. Teaching of undergraduate and postgraduate medical students, UCL


4. Clinical Supervisor for surgical trainees in renal transplantation.



Appointments
2013 – 2017 NIHR Clinical Lecturer & Honorary Specialist Registrar Department of Surgery (Transplantation) Cambridge University, United Kingdom
2011 – 2013 Specialist Registrar Department of General Surgery Luton & Dunstable Hospital NHS Trust, United Kingdom
2008 – 2011 Wellcome Trust Clinical Research Training Fellow Department of Surgery (Transplantation) Cambridge University, United Kingdom
2007 – 2008 Academic Clinical Fellow & Honorary Specialist Registrar Department of Surgery (Transplantation) Cambridge University, United Kingdom
2006 – 2007 Specialist Registrar Department of Cardiothoracic Surgery Guy's and St Thomas' NHS Foundation Trust, United Kingdom
2004 – 2006 Specialist Registrar Department of Cardiothoracic Surgery King's College Hospital NHS Foundation Trust, United Kingdom
2002 – 2004 Clinical Research Fellow Department of Cardiothoracic Surgery St. George's University Hospital, United Kingdom
2000 – 2002 Senior House Officer SHO Surgical Rotation (Eastern Deanery) Cambridge University Hospital & Papworth NHS Trust, United Kingdom
Academic Background
2015 FRCS Fellow Of The Royal College Of Surgeons – Surgery Royal College of Surgeons of England
2012 PhD Doctor of Philosophy – Surgery University of Cambridge
2006 MD Doctor of Medicine – Cardiological Sciences St George's Hospital Medical School
2000 MA Master of Arts – Pathology University of Cambridge
1998 MB BChir Bachelor of Medicine/ Bachelor of Surgery – Clinical Medicine University of Cambridge
1996 BA Bachelor of Arts – Pathology University of Cambridge
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