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Dr Silvia Dragoni
G29
Institute of Ophthalmology
London
United Kingdom
Tel: 02076084067
Appointment
  • Research Associate
  • Institute of Ophthalmology
  • Faculty of Brain Sciences
Research Summary

Throughout my career my research has focused on studying endothelial cells in physiological and pathological conditions and the regulatory role of Vascular Endothelial Growth Factor (VEGF).

Currently, I am working on VEGF-induced permeability in the blood-brain and blood-retinal barriers. I have validated an ex-vivo retinal model in rats to measure acute permeability in the retina in real time. I established this model in mice for the first time and I am using it successfully to elucidate the VEGF pathway that leads to permeability in the brain and the retina. The aim of my future work is to dissect the leakage response and associated signalling mediated by VEGFR2 in neural endothelial cells depending in its intracellular localisation, dimerization status and association with co-receptors or distinct signalling platforms.

Teaching Summary

2008 - 2010: Tutor of human anatomy for BSc students at the University of Pavia, Italy – 20 hours of teaching/year

Appointments
01-OCT-2019 Senior Research Fellow Institute of Ophthalmology UCL, United Kingdom
Academic Background
2014 PhD Doctor of Philosophy – Physiology Universita degli Studi di Pavia
2010 MSc Master of Science – Experimental Biology Universita degli Studi di Pavia
2008 BSc Bachelor of Science – Biological Sciences Universita degli Studi di Pavia
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