My current research interests are centred on the biochemical and metabolic responses to surgery and critical illness in infants and children. To these ends, we have established an active research group in the Paediatric Surgery unit undertaking a variety of basic science and applied clinical investigations. Recently, we have run several multi-centre and single-centre randomised clinical trials in Paediatric Surgery. I have also established a stable-isotope facility in the Institute of Child Health to undertake nutritional and body composition studies.