Simon Faithfull's work uses video, performance, drawing and text to explore and report back from the planet on which he finds himself. Different scales of time and space have become a theme within his investigations - often using his own body as kind of measuring stick, or his own subjective gaze as a recording device.

In 2019, the solo exhibition 'Fathom' at The Exchange, Penzance brought together a series of works that explores our relationship with a mostly liquid planet. Also in 2019 at The Natural History Museum in Berlin, the installation: 'An Arbitrary Taxonomy of Birds' used 120 specimens to create eccentric new taxonomies such as: 'Those who fit on my palm' and the first part of a permanent public-artwork for Cambridge University: 'Erratic #1' was unveiled.  

In 2009 his exhibition at British Film Institute brought together his Escape Vehicle series including the journey of a domestic chair as it travelled to the edge of space beneath a weather balloon. 2011 saw the launch of Limbo his web and social-media based artwork which delivers his drawings live to a world-wide audience.

Past work includes 'Antarctica Dispatches' - daily drawings dispatched live from Antarctica, Fake Moon - an intervention in the night sky of Bristol, 'Liverpool-to-Liverpool' - a permanent public artwork for the city of Liverpool that sets into paving-stone the drawings from a journey by containership from Liverpool to Canada.