UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
 More search options
Dr Sonja Hofer
21 University Street
Rockefeller Building, room 322
London
WC1E 6DE
Tel: +44 (0)20 7679 6381
Appointment
  • Reader in Neural Circuits and Behaviour
  • The Sainsbury Wellcome Centre
  • Faculty of Life Sciences
Biography

Dr. Sonja Hofer graduated in 2002 with a degree in Biology from the Technical University Munich.She completed her PhD and short postdoctoral studies with Mark Huebener and Tobias Bonhoeffer at teh Max Planck Institute of Neurobiology in Martinsried, Germany. Following a second postdoc with Thomas Mrsic-Flogel at UCL with funding from the Humboldt Foundation and EMBO, she was awarded a Wellcome Trust Research Career Development Fellowship in 2011 to establish her independent research group.

Research Themes
Research Summary

Our brains constantly have to adapt to changes in the environment. Therefore neuronal circuits cannot be hardwired, but require the capacity to change, and to integrate and store new information about the world around us. This is especially important during development when circuits are first set up, but also later in life to enable learning and memory formation. Learning alters our perceptions, cognition and behaviour by modifying neuronal circuits within and between different brain regions. Understanding how this happens is crucial for understanding normal brain function, and for devising therapeutic approaches for correcting disorders of infromation storage and retrieval such as dementia. Yet the mechanisms of learning in the intact brain are not well understood. How new information is stored in neuronal circuits and how new experiences, which are behaviourally relevant for the animal, alter single cells, their connections and the flow of information through neuronal networks, remain fundamental questions in neuroscience.

In my lab we are studying the mechanisms by which neocortical circuits give rise to sensations, how these circuits are set up during development and how they are changed and shaped by new experiences and learning. Using the mouse visual cortex as a model system we are emplying state of the art in vivo imaging of function and structure, electrophysiological and genetic techniques to visualize neurons, their activity and their synapses in the intact brain and follow changes over time while animals are learning or making new experiences.

Please report any queries concerning the data shown on this page to https://www.ucl.ac.uk/hr/helpdesk/helpdesk_web_form.php
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by