Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
 More search options
Prof Shin-Ichi Ohnuma
Institute of Ophthalmology, UCL
11-43 Bath Street
Prof Shin-Ichi Ohnuma profile picture
  • Professor
  • Institute of Ophthalmology
  • Faculty of Brain Sciences
Research Groups
Research Themes
Research Summary

Embryonic retina is formed through a combination of multiple developmental processes including neural induction, eye field specification, eye cup formation, cell fate determination, lamination, and differentiation. Our aim is to understand the detailed molecular mechanism of whole retinogenesis. In particular, our main focus of research is on the mechanism of co-ordination of cell cycle regulation with developmental processes. Although the cell cycle needs to be co-ordinated with many aspects of developmental processes, and the defects of the co-ordination are the causes of many human diseases - such as cancer and some retinal disorders - little is known about the mechanism. To determine the mechanism, we use the amphibian retina as a model system. This system is ideal for detailed and fast functional analysis of retinogenesis. Through a combination of in vivo and in vitro approaches, our group is actively searching novel genes

Prof. Ohnuma aims to understand molecular mechanisms underlying human diseases through combination of in animal models, cell biology, and bio-informatics. He has been studying various human diseases from cancer to eye diseases. In particular, he is interested in age-related diseases including AMD, RP, glaucoma, and various cancers. Also, he is interested in construction of functional eye using retinal stem cells both in vivo and in vitro. Through these study, he aims to develop novel diagnosis and treatments of human diseases.

Teaching Summary

Prof. Ohnuma is Director of PhD programme of the Sensory System, Technology, and Therapies (SenSyt). Also, he works for the Biology of Vision MSc and Cancer MSc.

Please report any queries concerning the data shown on this page to https://www.ucl.ac.uk/hr/helpdesk/helpdesk_web_form.php
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by