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Dr Scott Roberts
Division of Surgery and Interventional Science
  • Honorary Senior Lecturer
  • Department of Ortho and MSK Science
  • Div of Surgery & Interventional Sci
  • Faculty of Medical Sciences

Dr. Roberts obtained his PhD from the Roslin Institute (University of Edinburgh) where he investigated the biochemical events surrounding bone formation with a view to developing novel treatments for skeletal disease. Specifically, he investigated the role of a newly discovered enzyme, PHOSPHO1, in matrix mineralisation. Following this, he undertook postdoctoral training in the field of stem cell biology at the University of Nottingham where he analysed specific differences in the osteogenic differentiation capacity of adult progenitor and embryonic stem cells. Subsequently, in 2009 Dr. Roberts moved to the KU Leuven to establish a research track investigating conditions that could define and enhance the ability of skeletal precursors to form tissues in vivo. During his time here Dr. Roberts was awarded a fellowship from the Scientific Research Council of Flanders (Fonds Wetenschappelijk Onderzoek – Vlaanderen). In September 2013, Dr. Roberts was recruited to form a research group at the UCL Institute of Orthopaedics and Musculoskeletal Science, University College London (UCL). In January 2016 Dr Roberts was recruited to UCB Pharma as a Senior Principal Scientist. During his time at UCB Pharma Dr Roberts identified musculoskeletal drug targets and led subsequent drug discovery efforts. Furthermore, he supported the development of Bimekizumab and Romosozumab clinical programs through the contribution of insight/data on skeletal biology/disease. Dr Roberts was also appointed as Honorary Senior Lecturer at UCL in January 2016. In August 2019 Dr Roberts was appointed Senior Lecturer in Translational Musculoskeletal Research at the Royal Veterinary College, University of London.

Research Themes
Research Summary

Dr. Roberts’ research group aims to define the mechanisms of musculoskeletal development, disease and repair. The overall goal of his research is to identify and target cells and pathways to control bone and cartilage regeneration.  Dr. Roberts also has a long-standing interest in creating laboratory-grown models of skeletal tissues for the testing of biopharmaceuticals and compounds that may have applications to skeletal disease.

Teaching Summary

Dr. Roberts was the module lead for ‘Musculoskeletal Biology I (MSc in Musculoskeletal Science)’ and ‘Skeletal Tissue Biology (iBSc in Orthopaedic Science)’. Dr. Roberts also lectures on the 'Stem Cells and Regenerative Medicine' module and other courses throughout UCL.

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