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Dr Siyin Liu
Dr Siyin Liu profile picture
  • MRC Clinical Research Training Fellow (NR_Shane Liu)
  • Institute of Ophthalmology
  • Faculty of Brain Sciences

I am currently an MRC/Fight for Sight Clinical Research Training Fellow at the Institute of Ophthalmology. Prior to this role, I was an NIHR Academic Clinical Fellow and an Ophthalmology Registrar.

Research Themes
Research Summary

My research focuses on integrating molecular discoveries with clinical knowledge to improve patient outcomes. My present work aims at gaining a deeper understanding of the genetic factors that drive the onset and progression of Fuchs' Endothelial Corneal Dystrophy (FECD), the most prevalent short-tandem repeat expansion-associated disorder characterised in humans to date.

Using innovative genotyping techniques and advanced clinical imaging, we aim to discover new molecular insights with clinical relevance, which will ultimately allow for the development of decision support systems that can help to guide personalized medicine and improve risk stratification approaches.

My project is supervised by Associate Professor Alice Davidson, Dr Nikolas Pontikos, Professor Stephen Tuft, with additional support from collaborators Professor Darren Monckton, Professor Petra Liskova, and Dr Kirithika Muthusamy.

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