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Dr Toryn Poolman
Appointment
- Teaching Fellow in Molecular Biosciences
- Structural & Molecular Biology
- Div of Biosciences
- Faculty of Life Sciences
Research Themes
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Research Summary
My previous research was focused on trying to
understand how steroids work and how they interact with our body clock.
Cortisol, a hormone released from the adrenal glands peaks in the early morning
(the wakening hormone) and is virtually absent in the evening. Corticosteroids
(a collective name for steroid hormones produced by the adrenal gland,
including glucocorticoids and mineralocorticoids) have powerful anti-inflammatory
and metabolic effects, which are the template for synthetic steroids used to
treat inflammatory diseases, such as rheumatoid arthritis and asthma; however,
their use is hindered by severe side effects. My interests are in
using techniques to measure changes in all genes or proteins, using next
generation sequencing or mass spectrometry. I am particularly interested
in all aspects of data science for education and research (mainly using the R
programming language), using machine learning and other techniques to understand
complex datasets
Appointments
| 01-AUG-2018 – 28-JUN-2020 | Research associate | Oxford Centre for Diabetes, Endocrinology and Metabolism | University of Oxford, United Kingdom |
| 01-MAR-2011 – 01-AUG-2018 | Research associate | Faculty of Biology, Medicine and Health | University of Manchester, United Kingdom |
| 11-SEP-2006 – 01-MAR-2011 | Project Team leader | Technology Development | Health Protection Agency-Porton Down, United Kingdom |
