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Dr Tina Shah
Farr Institute
222 Euston Road
Tel: 020 35495587
Dr Tina Shah profile picture
  • Research Fellow
  • Population Science & Experimental Medicine
  • Institute of Cardiovascular Science
  • Faculty of Pop Health Sciences

Tina’s background is in genetics, having completed an undergraduate degree in Human Genetics at UCL, and going on to attain a PhD in Professor Hingorani’s laboratory in cardiovascular genetics. The focus of her PhD was in evaluating the role of C-reactive protein in the prediction and pathogenesis of coronary disease. During her PhD and postdoctoral work, she has focussed on a number of genetic and epidemiological approaches, including integrating information on genotype and/or phenotypes (including detailed information on blood biomarkers) in large population studies using meta-analysis, to address several fundamental issues in cardiovascular disease (CVD) including:

  • the utility of certain novel biomarkers (including CRP) for prediction of CVD events
  • the causal relevance of certain novel biomarkers in atherosclerosis and CVD
  • the mechanisms underlying the associations between single nucleotide variation and CVD risk uncovered recently by genome wide association studies (GWAS)

Research Summary

Tina continues to pursue her interest in cardiovascular genetics as a postdoctoral fellow in the Genetic Epidemiology group, utilising relevant genetic and epidemiological approaches. She is involved in collaborations including the University College-London School-Edinburgh-Bristol (UCLEB) Consortium, investigating genes and biomarkers involved in cardiovascular disease, as well as the Multimorbidity Mechanisms and Therapeutics Research Collaborative (MMTRC), which brings patients, carers, scientists and clinicians together to address the problem of multimorbidity. The unique properties of these consortia provide an opportunity to investigate genetic determinants of risk factors for disease. Integration of genotype, biomarker and disease outcome data can provide insight into disease mechanisms and potential therapeutic targets.

Teaching Summary

Tina is a module organiser for GENE0008: Genomics and DrugDevelopment as part of the MSc on Genetics of Human Disease.

Academic Background
2007   Doctor of Philosophy University College London
2002   Bachelor of Science University College London
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