As an undergraduate, I studied Molecular Genetics at Kings College London. I obtained my PhD at University College London on the effects of nutritional programming on islet-cell function and the key pancreatic glucose regulatory enzyme glucokinase. My research led to a publication and I won the Jean Rey prize in nutrition at the European Society for Paediatric Gastroenterology Hepatology & Nutritionmeeting in 2002.  After time out to travel the world (on a shoestring), I took up an EU funded post-doctoral position on the SAFE project the UCL Institute of Child Health on the proteomic investigation of maternal plasma for biomarkers of Down syndrome affected pregnancies which resulted in the discovery of 2 new biomarkers which were published and patented. Since this EU post, I developed core skills in proteomics, bioinformatics, mass spectrometry, and clinical assay development with a focus on novel biomarker discovery. I have been instrumental in developing the UCL Biological Mass Spectrometry Centre into the largest translational mass spectrometry platform at UCL. I became a GOSH BRC Senior ResearchAssociate in the Inborn Errors of metabolism section of the Genetics and Genomic Medicine department at ICH.  As a principal investigator, I lead translational research into lysosomal storage disorders developing novel biomarkers for treatment response and understanding disease mechanisms behind biomarker changes