UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at http://www.ucl.ac.uk/finance/research/post_award/post_award_contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
 More search options
Dr Wei-Li Di
30 Guilford Street
London
London
WC1N 1EH
Fax: 020 78138494
Appointment
  • Senior Lecturer
  • ICH Infect, Imm, Infla. & Physio Med
  • UCL GOS Institute of Child Health
  • Faculty of Pop Health Sciences
Research Summary

My interests are on rare skin diseases such as Netherton syndrome and a far more common disease atopic eczema. I want, through my research, to understand the patho-mechanisms underlying these conditions and develop more specific treatments for these diseases.

I have been studying the relationship of dysfunctional skin barrier and serine protease activity in atopic eczema, and developing a specific molecule to control the activity of serine protease activity. We are expecting that the outcomes of the research will potentially lead to treatment by offering a new way to attack the skin barrier function defect. We also hope that the research can provide new insight into how proteases contribute to skin pathology.  

In addition to this, our research team has been on the development of gene therapy strategies for genetic skin diseases and the research results have directly led to the initiation of translational developments for first in man gene therapy studies. We undertake GMP production of lentiviral skin grafts, and are well placed to lead the field in this area.


Academic Background
1996 PhD Doctor of Philosophy Queen Mary College, University of London
1983 MBBS Bachelor of Medicine/Bachelor of Surgery – Clinical Medicine Shanghai Medical University
Please report any queries concerning the data shown on this page to https://www.ucl.ac.uk/hr/helpdesk/helpdesk_web_form.php
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by