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Dr John Ioannou
Room 411
4th floor Rayne Institute
5 University Street
Dr John Ioannou profile picture
  • Honorary Reader
  • Div of Medicine
  • Faculty of Medical Sciences
Studied medicine at the Royal London Hospital Medical College and qualified in 1994. During specialist training in Rheumatology I was awarded an Arthritis Research UK Clinical Research Fellowship in 2002 during which I completed a PhD relating to the development of a novel peptide for therapeutic use in the antiphospholipid syndrome. After becoming an Honorary Consultant at UCLH in 2006, I was awarded an Arthritis Research UK Clinician Scientist Fellowship during which I spent two years overseas within the University of New South Wales undertaking further ground-breaking research in the antiphospholipid syndrome (2007-2009). Upon returning to ULC/UCLH I now lead on developing a programme of research in Adolescent Rheumatology, whilst also continuing my basic science research programme in APS and lupus.
Research Summary

My research is currently focussed on two broad themes: 1. Leading the development of a research programme in Adolescent Rheumatology. This involves the creation of 'research' pathways that interface between the paediatric and adult research centres at UCL to allow for streamlined transitional research in adolescents with arthritis that spans the whole adolescent age range. Translational basic science projects in autoimmune rheumatic diseases that target adolescents such as enthesitis related arthritis and juvenile onset systemic lupus erythemotsus are being targeted in particular. Also clinical trials in adolescents are now being set up at UCL/UCLH as well as active engagement in National Cohort Studies. 2. Basic science research into the pathogenesis of the antiphospholipid syndrome (APS) and lupus. I am co-PI on an Arthritis Research UK Programme grant that is investigating various molecular pathways that mediate pathogenesis in APS as well as partnering with a Biotech company to develop a novel recombinant peptide as a therapeutic. The mechanisms of cardiac injury are also being explored in lupus with a project investigating the relevance of ischemic-reperfusion injury in this disease.

Teaching Summary
I co-run a teaching firm with Professor Isenberg - teaching first year clinical medical students. Also examine for medical finals exam and talk at UCL MSc courses on Paediatric Rheumatology. Lecture regularly on PACES courses.
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