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Mother's preferences and willingness to pay for human papillomavirus vaccination for their daughters: a discrete choice experiment in Hong Kong
Cervical cancer is the tenth most common cancer in Hong Kong (HK) with 358 new cases and 128 related deaths in 2008. Two vaccines are available that offer protection against various strains of human pappillomavirus (HPV), which is associated with 99.7 percent of cervical cancers. In vaccination programmes, where effectiveness relies heavily on achieving high uptake in the target population, identification of factors that influence compliance is important. Objective: The objective of this study is to illicit consumers' preferences for different HPV vaccine attributes and their maximum willingness-to-pay (WTP) for the HPV vaccine in HK. Similar studies have been conducted overseas and comparisons will be made between the preferences of these populations with the HK population. Design: A dicrete choice experiment (DCE) surveying mothers with at least one daughter aged 8-17 years who have not received a HPV vaccination will be conducted using stratified sampling. Main Outcome measures: Mothers's preferences for protection against cervical cancer, protection duration, side-effects and out-of-pocket cost will be illicited. Regression coefficients represent WTP for extra benefit for a positive change in each attribute level. Data Analysis: Random-effects probit regression models will be used to adjust for similarity between participants adminstering the multiple number of choice sets. Log-likelihood and pseudo R-squares will be used to inform the goodness-of-fit of our regression models. Expected Results: The most and least important attributes will be identified by regression models. The estimated value of consumer benefits as measured by the WTP for the HPV vaccine will be estimated. The relative importance of various HPV vaccine attributes will be comparable to studies from other counties.
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