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Predicting skull growth in craniosynostosis for improved surgical treatment
The human skull consists of many bones that are joined together along their edges by dense soft tissues called sutures. The sutures are designed to give the bones flexibility for birth and to allow the skull to expand and grow as the brain enlarges. Once the brain and skull have reached their full adult size, the sutures fuse together to create a single bony structure. Premature closure of the sutures (craniosynostosis) is a medical condition that occurs in 1 in 2500 births and may result in functional abnormalities of the brain, breathing, feeding and vision unless there is surgical intervention. However, even after intervention, some children redevelop raised intercranial pressure requiring further surgical procedure. The aim of this research project is to understand how the biomechanical forces (especially from the growing brain) interact with the soft tissue structures and individual bone plates to shape the skulls of infants that develop craniosynostosis. The long term goal of the work is to provide advice to surgeons on when to operate and how best to manage the condition from a biomechanical point of view to ensure the best possible outcome for the child.
2 Researchers
  • Dept of Mechanical Engineering
  • Developmental Biology & Cancer Dept
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Status: Active
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