Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
The design and synthesis of photoaffinity labelled antagonists of the GABAA ion channel
The GABAA receptor is a chloride ion channel which has gamma-aminobutyric acid as its activating ligand. We are synthesising new antagonists that will, when irradiated with a UV light, covalently attach to the receptor completely blocking the active site. We want to then observe how the cell recovers its receptor activity - through digesting the receptor and replacing it with a new functional one. In this way we will gain new insights in to the ‘life cycle’ of receptors on the cells surface.
1 Researchers
 More search options
Status: Active
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by