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Catalytic Asymmetric Synthesis
Asymmetric synthesis, or the ability to synthesise a compound in one, or predominantly one enantiomerically pure form, is of great contemporary importance, partly because single enantiomers find application in numerous areas including pharmaceuticals, biological and medicinal chemistry, and materials science. The search is on for new chiral catalysts that will give compounds of high optical purity, preferably in large-scale processes. Within this site we disclose new amine catalysts that switch their enantiomeric bias simply upon N-methylation.
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