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Herb-Drug Interactions in African and South American countries
A large percentage of the African and South American population depend on herbal medicinal products for their disease management. Chronic diseases like diabetes have been identified as conditions in which there is a high incidence of herb use amongst patients, which are very often co-administered with their prescription drugs. Unfortunately, there is little or no information about investigations into possible herb-drug interactions for these herbal products. There is therefore the attendant risk of clinical inefficacy or clinical failure due to unidentified pharmacodynamic or pharmacokinetic interactions, with serious implications for drug safety. To address this dearth of information, aqueous extracts of samples of medicinal plants traditionally used in Nigeria and Brasil are being investigated in in-vitro pharmacokinetic interaction studies.
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