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Cancer Research UK Biomedical Structure Group
The Cancer Research UK Biomolecular Structure Group, works on the structure nucleic acids and their interaction with small molecules and proteins. Its approach is to analyse the molecular structures of nucleic acids and their complexes by means of X-ray crystallography and molecular modelling/simulation methods. This knowledge is applied to the rational design of novel small-molecule inhibitors for potential use as selective anticancer agents. The group is particularly well-known for its work on the DNA quadruplex.
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Current Research Activities
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

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