The Wellcome EPSRC Centre for Interventional and Surgical Sciences at UCL brings together a wide team of engineering and clinical experts working to develop new surgical technologies. The Centre is based at Charles Bell House. The advances of the Centre will create an intuitive and highly personalised surgical platform that enables more precise, less invasive procedures. Greater precision also means more patients will be viable for complicated but life-altering surgery and those treated will benefit from safer, more localised treatments and a shorter recovery time in hospital. The research is being developed with a wide range of clinical applications in mind, including vascular, paediatric, ophthalmic, neurological and prostate surgical interventions. In particular, the Centre will advance engineering sciences in intraoperative imaging and sensing, data fusion and extraction, human-technology interfaces, tissue modelling, interventional instrumentation and surgical navigation. Three fundamental research themes will link the Centre’s interdisciplinary and cross-faculty groups: · Physiological Navigation: Fusing anatomical, physiological and pathological information for real-time guidance and monitoring · Clinician Experience: Optimising the cognitive and ergonomic workload of the clinical team · Precision Instrumentation: Designing interventional devices that both sense physiological/pathological information and interact with tissue to deliver therapy All research themes are supported by a clear translation strategy to support concept-to-product research for maximum impact, made possible by the innovation support themes: · Health Technology Assessment: Evaluating the clinical impact of the Centre’s technology and relying on our hub-and-spoke model with key clinical satellites and our international partners · System Integration: Linking our fundamental research themes together and ensuring sustainability and scalability of our developments · Quality Management: Implementing best practice in our design, development and evaluation work to ensure safety of the devices we translate to the clinic and lower the barrier of technology transfer