The Clinical and Molecular Genetics Unit (CMGU) comprises a critical mass of more than 50 clinical and basic science staff with a common interest in the genetic and epigenetic regulation of human development and disease. Our goals are to: Understand the molecular, genetic and developmental aetiology of a range of single gene disorders, syndromes and complex traits in humans Develop new tests for diagnosing and monitoring these conditions Translate our research findings into improved care for children, adults and families