Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
High-risk human papillomavirus (HPV) infection and cervical cancer prevention in Britain: Evidence of differential uptake of interventions from a probability survey
  • Publication Type:
    Journal article
  • Authors:
    Tanton C, Soldan K, Beddows S, Mercer CH, Waller J, Field N, Clifton S, Copas AJ, Panwar K, Manyenga P, Da Silva F, Wellings K, Ison CA, Johnson AM, Sonnenberg P
  • Publication date:
  • Pagination:
    842, 853
  • Journal:
    Cancer Epidemiol Biomarkers Prev
  • Volume:
  • Status:
  • PII:
  • Language:
  • Notes:
    Copyright © 2015 American Association for Cancer Research.
Background: The third British National Survey of Sexual Attitudes and Lifestyles (Natsal-3) provides an opportunity to explore high-risk human papillomavirus (HR-HPV), and uptake of cervical screening and HPV vaccination in the general population. Methods: Natsal-3, a probability sample survey of men and women aged 16-74, resident in Britain, interviewed 8869 women in 2010-12. We explored risk factors for HR-HPV (in urine from 2569 sexually-experienced women aged 16-44), non-attendance for cervical screening in the past 5 years and non-completion of HPV catch-up vaccination. Results: HR-HPV was associated with increasing numbers of lifetime partners, younger age, increasing area-level deprivation and smoking. Screening non-attendance was associated with younger and older age, increasing area-level deprivation (age-adjusted odds ratio 1.91, 95% confidence interval, 1.48 to 2.47 for living in most vs. least deprived two quintiles), Asian/Asian British ethnicity (1.96, 1.32 to 2.90), smoking (1.97, 1.57 to 2.47) and reporting no partner in the past 5 years (2.45, 1.67 to 3.61 vs. 1 partner) but not with HR-HPV (1.35, 0.79 to 2.31). Lower uptake of HPV catch-up vaccination was associated with increasing area-level deprivation, non-white ethnicity, smoking and increasing lifetime partners. Conclusions: Socio-economic markers and smoking were associated with HR-HPV positivity, non-attendance for cervical screening and non-completion of catch-up HPV vaccination. Impact: The cervical screening programme needs to engage those missing HPV catch-up vaccination to avoid a potential widening of cervical cancer disparities in these cohorts. As some screening non-attenders are at low-risk for HR-HPV, tailored approaches may be appropriate to increase screening among higher-risk women.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers Show More
Institute for Global Health
Infection & Population Health
Infection & Population Health
Infection & Population Health
Infection & Population Health
Epidemiology & Public Health
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by