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Publication Detail
Use of the Fisher Information Matrix to optimize the acquisition protocol for a D-SPECT system
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Conference Proceeding
  • Authors:
    Fuin N, Pedemonte S, Arridge S, Ourselin S, Hutton BF
  • Publication date:
    01/12/2012
  • Pagination:
    2137, 2142
  • Journal:
    IEEE Nuclear Science Symposium Conference Record
  • Status:
    Published
  • Print ISSN:
    1095-7863
Abstract
The design of the D-SPECT system is based on compact CZT solid state detectors units that permit movements that would not be achievable with conventional gamma cameras. This new design permits to overcome some inherent SPECT limitations allowing for a region-centric acquisition. By choosing to spend more time directing the detector heads towards a region of interest (ROI), one can allocate more time to collect data from this region at the expense of collecting fewer data from less important regions. However, changing the detector angular movements allowing for a non uniform scanning pattern, the interdependence in the information changes and the D-SPECT system response may be highly shift-variant. In order to be able to compare a set of candidate scanning patterns (for a given activity distribution) a method is needed, that quantifies the information gain. © 2012 IEEE.
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