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Publication Detail
Molecular Mechanisms of Eye Degeneration in Cavefish
  • Publication Type:
    Chapter
  • Authors:
    Yamamoto Y
  • Publisher:
    Elsevier Academic
  • Publication date:
    12/10/2015
  • Place of publication:
    Amsterdam
  • Pagination:
    175, 189
  • Chapter number:
    9
  • Edition:
    1st
  • Editors:
    Keene AR,Yoshizawa M,McGaugh S
  • ISBN-13:
    9780128021484
  • Medium:
    Print
  • Status:
    Published
  • Book title:
    Biology and Evolution of the Mexican Cavefish
  • Language:
    English
  • Translators:
    not aplicable
  • Series editors:
    not aplicable
  • Keywords:
    Astyanax, cavefish, eye degeneration, lens, natural selection, energy conservation, trade-off, neutral mutation, genetic drift, pleiotropy, evolution
  • Addresses:
    UCL
    London
Abstract
Many animals have lost their eyes after dwelling in a dark environment for millions of years. The molecular and evolutionary mechanisms behind this eye loss are still not clear. The Mexican tetra, Astyanax fasciatus mexicanus is one of the best animal models for trying to solve this mystery. This chapter summarizes molecular mechanisms of eye degeneration during development. The molecular mechanisms behind eye degeneration could provide some hints to understand the evolutionally forces implicated in eye loss in this species.
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