UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
Air pollution and nonmalignant respiratory mortality in 16 cohorts within the ESCAPE project
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Dimakopoulou K, Samoli E, Beelen R, Stafoggia M, Andersen ZJ, Hoffmann B, Fischer P, Nieuwenhuijsen M, Vineis P, Xun W, Hoek G, Raaschou-Nielsen O, Oudin A, Forsberg B, Modig L, Jousilahti P, Lanki T, Turunen A, Oftedal B, Nafstad P, Schwarze PE, Penell J, Fratiglioni L, Andersson N, Pedersen N, Korek M, De Faire U, Eriksen KT, Tjønneland A, Becker T, Wang M, Bueno-De-Mesquita B, Tsai MY, Eeftens M, Peeters PH, Meliefste K, Marcon A, Krämer U, Kuhlbusch TAJ, Vossoughi M, Key T, De Hoogh K, Hampel R, Peters A, Heinrich J, Weinmayr G, Concin H, Nagel G, Ineichen A, Jacquemin B, Stempfelet M, Vilier A, Ricceri F, Sacerdote C, Pedeli X, Katsoulis M, Trichopoulou A, Brunekreef B, Katsouyanni K
  • Publication date:
    15/03/2014
  • Pagination:
    684, 696
  • Journal:
    American Journal of Respiratory and Critical Care Medicine
  • Volume:
    189
  • Issue:
    6
  • Status:
    Published
  • Print ISSN:
    1073-449X
Abstract
Rationale: Prospective cohort studies have shown that chronic exposure to particulate matter and traffic-related air pollution is associated with reduced survival. However, the effects on nonmalignant respiratory mortality are less studied, and the data reported are less consistent. Objectives: We have investigated the relationship of long-term exposure to air pollution and nonmalignant respiratory mortality in 16 cohorts with individual level data within the multicenter European Study of Cohorts for Air Pollution Effects (ESCAPE). Methods: Data from 16 ongoing cohort studies from Europe were used. The total number of subjects was 307,553. There were 1,559 respiratory deaths during follow-up. Measurements and Main Results: Air pollution exposure was estimated by land use regression models at the baseline residential addresses of study participants and traffic-proximity variables were derived from geographical databases following a standardized procedure within the ESCAPE study. Cohort-specific hazard ratios obtained by Cox proportional hazard models from standardized individual cohort analyses were combined using metaanalyses. We found no significant associations between air pollution exposure and nonmalignant respiratory mortality. Most hazard ratios were slightly below unity, with the exception of the traffic-proximity indicators. Conclusions: In this study of 16 cohorts, there was no association between air pollution exposure and nonmalignant respiratorymortality.Copyright © 2014 by the American Thoracic Society.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers
Author
Clinical Epidemiology
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by