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Publication Detail
White matter reorganization after stroke measured by Gaussian DTI, q-ball, and PAS MRI
  • Publication Type:
  • Authors:
    Jiang Q, Alexander DC, Ding GL, Zhang ZG, Pourabdollah S, Nejad D, Zhang L, Li L, Hu J, Bagherebadian H, Ewing JR, Chopp M
  • Publisher:
    International Society for Magnetic Resonance in
  • Publication date:
  • Place of publication:
    Berkeley, US
  • Pagination:
  • Published proceedings:
    International Society for Magnetic Resonance in Medicine 15th Annual Scientific Meeting and Exhibition: 2007 Proceedings
  • Status:
We investigated white matter remodeling after stroke using Gaussian diffusion tensor imaging (DTI), q-ball, persistent angle structure (PAS) MRI and gold standard immuno-histochemistry staining. We demonstrate that MRI fractional anisotropy (FA) identifies tissue with white matter reorganization, fiber orientation of axonal projections from Gaussian DTI, orientation distribution function (ODF) in q-ball, and PAS MRI detects changes of axonal orientation in the ischemic boundary region after stroke. PAS and ODF in q-ball provide the correct fiber crossing information in the layer between corpus callosum and cortex.
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