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Publication Detail
Determining material properties of the breast for image-guided surgery
  • Publication Type:
    Conference
  • Authors:
    Carter TJ, Tanner C, Hawkes DJ
  • Publication date:
    19/06/2009
  • Published proceedings:
    Progress in Biomedical Optics and Imaging - Proceedings of SPIE
  • Volume:
    7261
  • ISBN-13:
    9780819475121
  • Status:
    Published
  • Print ISSN:
    1605-7422
Abstract
We have previously proposed a system for image-guided breast surgery that compensates for the deformation of the breast during patient set-up. Since breast surgery is performed with the patient positioned supine, but MR imaging is performed with the patient positioned prone, a large soft tissue deformation must be accounted for. A biomechanical model can help to constrain the associated registrations. However the necessary material properties for breast tissue under such strains are not available in the literature. This paper describes a method to determine these properties. We first show that the stress-free or 'reference' state of an object can be approximated by submerging it in liquid of a similar density. MR images of the breast submerged in water and in a pendulous prone position are acquired. An intensity-based non-rigid image registration algorithm is used to establish point-by-point correspondence between these images. A finite element model of the breast is then constructed from the submerged images and the deformation to free-pendulous is simulated. The material properties for which the model deformation best fits the observed deformation are determined. Assuming neo-Hookean material properties, the initial shear moduli of fibroglandular and adipose tissue are found to be 0.4 kPa and 0.3 kPa respectively. © 2009 SPIE.
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