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Publication Detail
Quantification of blood flow from rotational angiography
  • Publication Type:
  • Authors:
    Waechter I, Bredno J, Barratt DC, Weese J, Hawkes DJ
  • Publication date:
  • Pagination:
    634, 641
  • Published proceedings:
    Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
  • Volume:
    4791 LNCS
  • Issue:
    PART 1
  • ISBN-13:
  • Status:
  • Print ISSN:
For assessment of cerebrovascular diseases, it is beneficial to obtain three-dimensional (3D) information on vessel morphology and hemodynamics. Rotational angiography is routinely used to determine the 3D geometry and we propose a method to exploit the same acquisition to determine the blood flow waveform and the mean volumetric flow rate. The method uses a model of contrast agent dispersion to determine the flow parameters from the spatial and temporal development of the contrast agent concentration, represented by a flow map. Furthermore, it also overcomes artifacts due to the rotation of the c-arm using a newly introduced reliability map. The method was validated on images from a computer simulation and from a phantom experiment. With a mean error of 11.0% for the mean volumetric flow rate and 15.3% for the blood flow waveform from the phantom experiments, we conclude that the method has the potential to give quantitative estimates of blood flow parameters during cerebrovascular interventions. © Springer-Verlag Berlin Heidelberg 2007.
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