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Publication Detail
Effects of respiratory liver motion on heating for gated and model-based motion-compensated high-intensity focused ultrasound ablation
  • Publication Type:
    Conference
  • Authors:
    Rijkhorst EJ, Rivens I, Ter Haar G, Hawkes D, Barratt D
  • Publication date:
    11/10/2011
  • Pagination:
    605, 612
  • Published proceedings:
    Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
  • Volume:
    6891 LNCS
  • Issue:
    PART 1
  • ISBN-13:
    9783642236228
  • Status:
    Published
  • Print ISSN:
    0302-9743
Abstract
Purpose: To quantify the effects of respiratory motion on high-intensity focused ultrasound heating of liver tissue by comparing the simulated ablation using a conventional respiratory gating versus a MR-model-based motion compensation approach. Methods: To measure liver motion, dynamic free-breathing abdominal MR scans were acquired for five volunteers. Deformable registration was used to calculate continuous motion models, and tissue heating at a moving single focus was computed in 3-D by solving the bioheat equation. Ablated volume ratios with respect to the static case, νab, were determined for a range of exposure times texp and heating rates r. Results: To achieve νab > 90% required texp < 0.5s and r > 120°C/s when gating, whereas texp < 1s and r > 60°C/s for motion-compensation. Conclusions: Accurate compensation for respiratory motion is important for efficient tissue ablation. Model-based motion compensation allows substantially lower heating rates than gating, reducing the risk of skin burns and focal boiling. © 2011 Springer-Verlag.
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