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Publication Detail
Regional variation of total sodium concentration in the healthy human brain
  • Publication Type:
    Conference
  • Authors:
    Prados Carrasco F, Solanky BS, Alves da Mota P, Cardoso MJ, Brownlee WJ, Riemer F, Miller DH, Golay X, Ourselin S, Wheeler-Kingshott CAM
  • Name of conference:
    International Society for Magnetic Resonance in Medicine (ISMRM) 24th Scientific Meeting and Exhibition
  • Conference place:
    Singapore
  • Conference start date:
    07/05/2016
  • Conference finish date:
    13/05/2016
  • Publisher URL:
Abstract
Non-invasive measurement of in vivo total sodium concentration (TSC) has been possible due to advances in sodium MRI at clinical field strengths. Changes in white and grey matter concentrations have been reported in a number of different diseases like Multiple Sclerosis. However, the presence of regional differences in normal healthy brain TSC has not been yet investigated. Here we use Geodesic Information Flow technique for computing per subject brain parcellations to allow differentiation of these areas and subsequently characterization of regional TSC in healthy controls.
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