UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
Reward motivation accelerates the onset of neural novelty signals in humans to 85 milliseconds.
Abstract
The neural responses that distinguish novel from familiar items in recognition memory tasks are remarkably fast in both humans and non-human primates. In humans, the earliest onsets of neural novelty effects emerge at about ~150-200ms after stimulus onset [1-5]. However, in recognition memory studies with non-human primates, novelty effects can arise as early as 70-80ms [6, 7]. Here, we address the possibility that this large species difference in onset latencies is caused experimentally by the necessity to use reward reinforcement to motivate the detection of novel or familiar items in non-human primates but not in humans. Using magnetoencephalography in humans, we show in two experiments that the onset of neural novelty signals is accelerated from ~200ms to ~85ms if correct recognition memory for either novel or familiar items is rewarded. Importantly, this acceleration is independent of whether it is the detection of the novel or the familiar scenes that is rewarded. Furthermore, this early novelty effect contributed to memory retrieval because neural reward responses, which were contingent upon novelty detection, followed ~100ms later. Thus, under the contextual influence of reward-motivation behaviorally relevant novelty signals emerge much faster than previously held possible in humans.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers
Author
Imaging Neuroscience
Author
Institute of Cognitive Neuroscience
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by