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Publication Detail
Inference of Tissue Haemoglobin Concentration From Stereo RGB
  • Publication Type:
  • Authors:
    Jones G, Clancy N, Arridge S, Elson D, stoyanov D
  • Publisher:
    Springer Verlag (Germany)
  • Publication date:
  • Published proceedings:
    Lecture Notes in Computer Science
  • Name of conference:
    Medical Imaging and Augmented Reality
  • Conference place:
    Bern, Switzerland
  • Conference start date:
  • Conference finish date:
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Multispectral imaging (MSI) can provide information about tissue oxygenation, perfusion and potentially function during surgery. In this paper we present a novel, near real-time technique for intrinsic measurements of total haemoglobin (THb) and blood oxygenation (SO2) in tissue using only RGB images from a stereo laparoscope. The high degree of spectral overlap between channels makes inference of haemoglobin concentration challenging, non-linear and under constrained. We decompose the problem into two constrained linear sub-problems and show that with Tikhonov regularisation the estimation significantly improves, giving robust estimation of the THb. We demonstrate by using the co-registered stereo image data from two cameras it is possible to get robust SO2 estimation as well. Our method is closed from, providing computational efficiency even with multiple cameras. The method we present requires only spectral response calibration of each camera, without modification of existing laparoscopic imaging hardware. We validate our technique on synthetic data from Monte Carlo simulation and further, in vivo, on a multispectral porcine data set.
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