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Publication Detail
Studies of G-quadruplexes formed within self-assembled DNA mini-circles
  • Publication Type:
    Journal article
  • Authors:
    Klejevskaja B, Pyne ALB, Reynolds M, Shivalingam A, Thorogate R, Hoogenboom BW, Ying L, Vilar R
  • Publisher:
    Royal Society of Chemistry (RSC)
  • Pagination:
    12454, 12457
  • Journal:
    Chemical Communications
  • Volume:
  • Issue:
  • Status:
    Published online
  • Print ISSN:
  • Language:

We have developed self-assembled DNA mini-circles that contain a G-quadruplex-forming sequence and demonstrate by FRET that the G-quadruplex unfolding kinetics are 10-fold slower than for the simpler 24-mer G-quadruplex that is commonly used for FRET experiments.

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