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Publication Detail
Recent advances in the treatment of systemic lupus erythematosus
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Review
  • Authors:
    Rodriguez-Garcia V, Sapeta Dias S, Isenberg D
  • Publication date:
    01/02/2014
  • Pagination:
    89, 100
  • Journal:
    International Journal of Clinical Rheumatology
  • Volume:
    9
  • Issue:
    1
  • Status:
    Published
  • Print ISSN:
    1758-4272
Abstract
Survival for patients with systemic lupus erythematosus has much improved in the last 50 years. Faster diagnosis, renal dialysis and transplant, and better general care (including lowering of blood pressure and treating osteoporosis) have had important roles in this. We have optimized the use of corticosteroids and conventional immunosuppressive drugs, reducing the side effects and improving efficacy. However, the progression to end-stage renal disease has not changed. The advent of targeted therapies using biologic agents has held great promise but because of the design of the trials, the results are disappointing and these drugs are not yet widely accepted. More and better designed trials are needed. © 2014 Future Medicine Ltd.
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