Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
Drug-induced vasculitis
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Journal Article
  • Authors:
    Taborda L, Amaral B, Isenberg D
  • Publication date:
  • Pagination:
    1075, 1078
  • Journal:
    Adverse Drug Reaction Bulletin
  • Issue:
  • Status:
  • Print ISSN:
Drug-induced vasculitis is an inflammatory vasculopathy associated with drugs of almost every class and accounting for approximately 3% of the vasculitides. Although small vessel disease limited to the skin is the most common form, involvement of blood vessels in virtually every organ system may occur. Given its similarity to other vasculitides and the absence of reliable confirmatory tests, it remains a diagnosis of exclusion. Cell-mediated and humoral immunity invariably play an important role in pathogenesis. To date, the most likely mechanism is related to the development of antineutrophil cytoplasmic autoantibodies. Withdrawal of the suspected causative drug is essential, but corticosteroids, immunosuppressive agents or, rarely, plasmapheresis may be necessary in multiorgan or life-threatening disease. The mortality is up to 10%. Copyright © Lippincott Williams & Wilkins.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by