Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
"Virus and Epidemic": Causal Knowledge Activates Prediction Error Circuitry.
Knowledge about cause and effect relationships (e.g., virus-epidemic) is essential for predicting changes in the environment, and anticipating the consequences of events and one’s own actions. While there is evidence that predictions and learning from prediction errors are instrumental in acquiring causal knowledge, it is unclear whether prediction error circuitry remains involved in the mental representation and evaluation of causal knowledge already stored in semantic memory. In a functional magnetic resonance imaging (fMRI) study, participants assessed whether pairs of words were causally related (e.g., virus-epidemic) or non-causally associated (e.g., emerald-ring). In a second fMRI study, a task cue prompted the participants to evaluate either the causal or the non-causal associative relationship between pairs of words. Causally related pairs elicited higher activity in orbitofrontal cortex, amygdala, striatum, and substantia nigra/ventral tegmental area (SN/VTA) than non-causally associated pairs. These regions were also more activated by the causal than by the associative task cue. This network overlaps with the mesolimbic and mesocortical dopaminergic network known to code prediction errors suggesting that prediction error processing might participate in assessments of causality even under conditions when it is not explicitly required to make predictions.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers
Institute of Cognitive Neuroscience
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by