UCL  IRIS
Institutional Research Information Service
UCL Logo
Please report any queries concerning the funding data grouped in the sections named "Externally Awarded" or "Internally Disbursed" (shown on the profile page) to your Research Finance Administrator. Your can find your Research Finance Administrator at https://www.ucl.ac.uk/finance/research/rs-contacts.php by entering your department
Please report any queries concerning the student data shown on the profile page to:

Email: portico-services@ucl.ac.uk

Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
Publication Detail
Current Advancements and Strategies in Tissue Engineering for Wound Healing: A Comprehensive Review.
  • Publication Type:
    Journal article
  • Publication Sub Type:
    Review
  • Authors:
    Ho J, Walsh C, Yue D, Dardik A, Cheema U
  • Publication date:
    01/06/2017
  • Pagination:
    191, 209
  • Journal:
    Advances in wound care
  • Volume:
    6
  • Issue:
    6
  • Medium:
    Print
  • Print ISSN:
    2162-1918
  • Language:
    eng
  • Addresses:
    UCL Division of Surgery and Interventional Sciences, UCL Institute for Orthopaedics and Musculoskeletal Sciences, University College London, London, United Kingdom.
Abstract
Significance: With an aging population leading to an increase in diabetes and associated cutaneous wounds, there is a pressing clinical need to improve wound-healing therapies. Recent Advances: Tissue engineering approaches for wound healing and skin regeneration have been developed over the past few decades. A review of current literature has identified common themes and strategies that are proving successful within the field: The delivery of cells, mainly mesenchymal stem cells, within scaffolds of the native matrix is one such strategy. We overview these approaches and give insights into mechanisms that aid wound healing in different clinical scenarios. Critical Issues: We discuss the importance of the biomimetic niche, and how recapitulating elements of the native microenvironment of cells can help direct cell behavior and fate. Future Directions: It is crucial that during the continued development of tissue engineering in wound repair, there is close collaboration between tissue engineers and clinicians to maintain the translational efficacy of this approach.
Publication data is maintained in RPS. Visit https://rps.ucl.ac.uk
 More search options
UCL Researchers
Author
Department of Ortho and MSK Science
Author
The Ear Institute
Author
Dept of Mechanical Engineering
University College London - Gower Street - London - WC1E 6BT Tel:+44 (0)20 7679 2000

© UCL 1999–2011

Search by